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Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors

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Injection-site & unknown long-term profile: Mild injection-site reactions can occur, and long-term human safety data are limited, so caution and monitoring are advised

Owners of dogs may report unilateral or bilateral lameness or paresis/paralysis, toe dragging, low tail or neck carriage, difficulties with rising, sitting or lying down, reluctance to jump or climb, urinary or faecal incontinence, and hyperesthesia or self-mutilation [11]

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